Dr. Andrea La Torre, MD
THE TREATMENT AGAINST INNER EAR HYDROPS: EFFECTIVE FOR TINNITUS, HEARING LOSS, VERTIGO, DIZZINESS, EAR FULLNESS, MENIERE'S DISEASE

by Dr. Andrea La Torre, M.D.
Otolaryngologist
ITALY

Updated: Wednesday, August 12, 2009

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Tinnitus, as well as sensorineural hearing loss (deafness), giddinesses, vertigo, dizziness or balance disorders and other ear symptoms like a feeling of pressure or fullness are all caused, in many patients affected by one of more of these complaints, by a reversible hydro-mechanical dysfunction in the inner ear and they are not always (or not only) the expression of a cochlear cells or nerves or vestibular receptors permanent damage as generally most of patients hear from their specialists. This can be well realized performing special and less known diagnostic tests to assess the functional status of the whole labyrinth (the other name of the inner ear) and listening a bit more to the features of their complaints... if we give the patients enough time to describe them completely.

We're talking about the same pathological mechanism (the so called "labirynthic hydrops"), well known and usually admitted by all only for Meniere's disease or syndrome.

But even when the symptoms are limited (i.e. only tinnitus and/or hearing loss or vertigo without hearing complaints and so on) the excess of inner ear fluids is still the main underlying cause in many patients who are still looking for a help.


WARNING: The information on this page is not intended to replace the advice of a ENT doctor. This page gives only the personal opinion of its author, well confirmed by medical direct experience and many years of medical scientific researches, but it's not approved or known by every ENT specialist .


THE TREATMENT AGAINST INNER EAR DISEASES

By means of a special treatment against the excess of the fluids in the inner ear (hydrops) that, as we know, is mainly regulated by an hormone (known as "vasopressin" or "antidiuretic hormone"- ADH), we can partially or completely recover many sensorineural hearing disorders, as well as tinnitus (buzz or whistle in the ear),but also giddiness / dizziness or balance complaints. This goal can be often reached even after many years from the beginning, and... even if, generally, most of the inner ear disorders are still considered "untreatable" by the majority of specialists.

Dr. La Torre's activity is directed to patients affected by one or more disorders from a inner ear dysfunction (tinnitus, sensorineural deafness, vertigo or other balance disorders, or with a previous diagnosis, but still searching a treatment, of typical Meniere's disease). In most of these patients hydrops can be directly suspected already collecting the clinical history of patient's troubles which are often described as fluctuating and not constant. This changeable situation can not be only due to a permanent damage, that could only produce, obviously, a permanent symptom. But even in case of a permanent symptom like i.e. a tinnitus heard always at the same loudness level, we can not diagnose a permanent damage or exclude a reversibility with the right treatment.

Success or failure of the special treatment we have conceived, which is the result of many years of intensive interdisciplinary clinical research, is mainly linked to the particular and present functional status of the ear of every single patient, wich can't be evaluated without carrying out special diagnostic tests other than the traditional ones. The peculiar psychological status of every single patient must be as well taken in account because psychological stress is often a main factor for the development of an ear hydrops and for the frequency of recurrent crisis.

Now, after more than ten years of clinical researches, involving thousands of patients studied in every possible way, even with special tests created or modified on this purpose, I don't feel the need anymore to investigate instrumentally the ear because, anyway, it's clear that the only possible effective treatment is the one against the inner ear fluids. The goal of my first meeting with the patient is to understand if he or she really needs a treatment, to evaluate his or her psycological conditions, and the real compliance to a possible treatment after full understanding of the disease and the treatment itself. This allow me to perform direct medical consultation with the patients in many different cities, to keep "low-cost" the consultation and the treatment itself and to propose even medical advice Internet-based using simply a webcam and skype.
But I strongly suggest to any specialist who desires to do something new on this subject to start his own diagnostic path to confirm, as I did for many years, what he or she is reading here. I will be glad to help any specialist all around the world to reach this goal with any information that can help.

The production of tinnitus or sensorineural deafness, giddiness / dizziness or disorders of balance can be basically the expression of one or more among three different pathological mechanisms: fluids excess in the inner ear (hydrops); permanent damages of the cochlear cells ; troubles with the acoustic or vestibular nerves.
Only in the first case of three (the hydrops) a treatment can be effective but, fortunately, this is the actual situation for at least
70% of patients. This situation is widely underestimated because, without performing a complete functional evaluation of the whole labyrinth and listening carefully to patient's complaints, the ENT specialist cannot always recognize the hydrops, so that the most frequent diagnosis the patients generally still receive is that there must be an "hypothetical" (but not actually shown) permanent damage of cells or nerves. The "logical" consequence is that the best suggestion the patient often receives is... "there's nothing we can do!"

Dealing with a "typical" Meniere's disease, the right treatment can always reduce the frequency and the lenght of the recurrent rotatory vertigo crises, as well as stop (in most of cases) the evolution of the hearing loss (it can be rather often reduced, partially or completely) and remove the feeling of fullness and pressure in the ear (a typical symptom of hydrops). There's no need, and until now we never had it for more than a thousand of Meniere's disease patients we have treated, at the level reached by therapeutical means and knowledge, to cut the vestibular nerve or to destroy the labirynth with ototoxyc drugs, even if those are nowadays the most proposed ways to prevent new crises. The rate of success with Meniere's disease tinnitus with the sole treatment against the hydrops, is generally high, but less predictable, because it depends of the residual functional status of the cochlear cells, which could be (but it's not the rule) partially but permanently damaged after many years of recurrent crises.

At the end of the evaluation we decide with the patient affected by an hearing (tinnitus or/and hearing loss) or balance disorder (giddiness, instability) or a full Meniere's Syndrome how his/her problem can be treated and above all, IF there's the need for a treatment considering that many patients only need to be reassured, because the symptoms are indeed very rare or not annoying at all.

Indeed, even when the diagnostic test do not show directly the presence of hydrops, or even if there's a strong clinical suspicion of an unrecoverable permanent damage, we could often reach significant improvements. The inner ear actual and present status, could indeed be better whatever is shown by the tests. In case of tinnitus or deafness, in example, cochlear cells can be intact, even if they're not "sufficiently working" because of the hydrops, and this could lead to a false "absence of response" at the specific functional tests.

One main goal of the treatment, in that case, is also to reach a diagnosis. Even if initial success is only partial or temporary we have shown, in any case, the reversibility of the dysfunction, that means that there was at least a component due to the excess of fluids and not coming from a permanent damage.

In case of failure, it could be possible, to deal with each problem (when the dysfunction is not, indeed, totally reversible) by means of other methods (like, for example, the TRT - Tinnitus Retraining Therapy or the vestibular rehabilitation, that must be taken in account when a balance disorder is caused by a permanent damage of the labirynthic receptors, indeed more rarely then what is generally diagnosed). But in that case after the failure of the treatment, that must be taken in account for not-fluctuating hearing losses or tinnitus not reversible after the treatment itself, we refer the patient to other centers.

In other words, the treatment can be effective for fluctuating tinnitus or hearing losses (deafness), recurrent vertigo crises or balance disorders, ear fullness, but a complete success can not be promised to everyone if we are dealing with permanent hearing loss or tinnitus. Indeed we try...and sometimes we reach an unexpected success. But it wouldn't be honest to say that "EVERY HEARING LOSS or TINNITUS can be cured". And before searching a contact for a date and to let you grow your illusion, it's very important, if your tinnitus or hearing loss is REALLY permanent without any change of loudness or loss, to understand well that. Even if it's true that every patient has the right to try to be treated, we can't say that every patient will have a sure benefit. Because our treatment cures the inner ear fluids excess. Real permanente damage (that we can suppose but it can't be certified) CAN'T BE YET TREATED. It's clear?

The main goal of the therapy we have conceived to deal with hydrops is mainly the regulation of the antidiuretic hormone release. It doesn't have any side effect.

But, how is this treatment pratically performed? It is based on many different therapeutical approaches:

- Fluids (water) overload, that must be associated to a special diet (not just the low-salt diet traditionally suggested for Meniere's disease) conceived by us, and successfully used since 1998 to prevent Meniere's disease recurrent crises. Why that? Because water is the main and the only available (nowadays) antidiuretic hormone antagonist! The special diet is mainly based on simple foods (meat or fish, vegetables, fruit). The diet itself is very hard but it's needed generally for only three/four weeks..

- A double intravenous treatment (in the second week of treatment) with an osmotic diuretic and steroids (without any risk for side effects or complicance). Steroids, if they are associated with a water overload, do not cause a water retention but, on the opposite, they have a diuretic effect, because they regulate the release of the antidiuretic hormone!!. The intravenous treatment (once a day for two days) is followed by a decresing dose treatment with steroids only, intramuscolar for other three days and then orally. The treatment can easily performed at your own home with the assistance of a nurse or a doctor.

- Treatment of stress and psychological factors (always needed because stress is an important sustaining condition) with an accurate counselling but even with drugs active on the brain (paroxetine, clonazepam, levosulpiride)The special treatment we propose in that case is characterized by low or none side effects (anyway not permanent) and a therapeutic effect (even without other treatments) directly on tinnitus and vertigo in many patients. But the main effect is on stress that can lead to an increased production of the antidiuretic hormon and by means of it to an increased hydrop in the inner ear.

How this treatment basically works?

1. IF we suppose that in the inner ear there is an excess of fluids

2. AND we know that fluids of the inner ear are under the regulation of the antidiuretic hormone (ADH) and the hydrops can be the result of a normal stimulation on a hypersensitive inner ear (due to different causes we can't know)

3. Even if we can't (yet) change the way the inner ear answers to ADH stimulation but we can control the release of the antidiuretic hormone to reduce the excess of fluids in the ear

There is a lot of scientific papers about the relationship between ear and ADH. Take a look clicking here.

Drugs with a specific activity against the ADH are not yet available for inner ear disorders. Tolvaptan is the name of an anti-ADH drug but it has not been studied enough for this purpose and it's not available for treating inner ear diseases.

The main and more effective way to control the ADH is to guarantee a constant water intake. But this can work only if we add to the water intake a special diet to control the quality of food intake, that can't be limited to salt restrictions. Overload of water intake without food intake modifications and restrictions is generally uneffective and potentially dangerous.

Our special diet is often sufficient, alone, to prevent the recurrent crises of a initial Meniere's disease and to avoid a worsening of the dysfunction.

But if we want to reduce the hydrops already developed and "blocked" inside the inner ear, then we often need an additional help. So we try to reduce the excess of fluids already present with an acute intensive treatment with an osmotic diuretic (that works at its best only if associated to an overload of water intake) and steroids, for their ability to regulate the ADH release but only if they are associated with water intake.

The treatment has indeed no risks or danger, but there are some counter indications (absolute or relative) that must be evaluated before we can propose the treatment, particularly to aged patients. Unfortunately the treatment is not actually an option for children but only for adult patients.

In any case our treatment is a short-period therapy that aims to show results (if a success can be achieved) in few weeks. A possible recurrence after time, even in case of success, must be taken in account because we don't erase the disease from the ear, but every eventual recurrence can be treated in an easy way having learned the treatment without the need to come back again to the doctor every time. In our experience, in most of patients a short period tratment can protect the ear for a long time. The main advantage of the treatment is that it's self-made without the need of many dates with the doctor but many contacts via phone, or webcam or mail are needed to check the results and to receive assistance in the first phase.


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